Naphthoflavone
Witryna12 lip 2013 · The reaction was stopped by the addition of 3 μM α-naphthoflavone (for CYP1A2) or 10 mM ketoconazole (for CYP3A4). CYP activity was evaluated by measuring the fluorescence of the fluorescent metabolite generated from each CYP enzyme-specific substrate. The fluorescence was measured using a microplate … Witryna20 gru 2024 · Beta-naphthoflavone induced apoptosis via JNK signaling pathway. Abstract Doxorubicin is one of the most effective chemotherapeutic agents available …
Naphthoflavone
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Witrynaβ-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and as such is an inducer of such detoxification enzymes as … WitrynaAnnie Hamel, ... Ray Proudlock, in Genetic Toxicology Testing, 2016. 4.6.16 S9 Fraction. Rats (usually Sprague-Dawley outbred) are pretreated with Aroclor 1254 or phenobarbital plus β-naphthoflavone to promote the levels of xenobiotic metabolizing enzymes [23–25].S9 fraction is conventionally prepared by homogenization of liver in isotonic …
WitrynaAldrich-N5757; alpha-Naphthoflavone; CAS No.: 604-59-1; Linear Formula: C19H12O2; Empirical Formula: C19H12O2; find related products, papers, technical documents, … WitrynaAldrich-N5757; alpha-Naphthoflavone; CAS No.: 604-59-1; Linear Formula: C19H12O2; Empirical Formula: C19H12O2; find related products, papers, technical documents ...
Witryna14 kwi 2024 · Α-naphthoflavone, quinidine, clomethiazole, ticlopidine, ketoconazole, and fluconazole were selected as specific inhibitors of CYP1A2, CYP2D22, CYP2E1, CYP2C37, CYP3A11, and CYP2C11, respectively (El-Sherbeni and El-Kadi, 2014; Xu et al., 2016). Forty-eight mice were randomly divided into eight groups of six mice each. Witryna19 sie 2004 · None of the beta-naphthoflavone derivatives were active. Various flavones substituted with a bromine, fluorine, or nitro-group at the 2′-, 3′- or 4′-position of the B …
Witrynaα-Naphthoflavone. Molecular Formula CHO. Average mass 272.297 Da. Monoisotopic mass 272.083740 Da. ChemSpider ID 11297.
Witryna12 gru 2024 · β-naphthoflavone (BNF) is both a synthetic flavonoid and a non-carcinogenic AhR ligand, often used as a positive control for AhR activation . Previous studies demonstrate that BNF upregulates the expression or activity of antioxidative enzymes, including glutathione peroxidase, quinone oxidoreductase-1, glutathione … jimmy choo denise flat sandalsjimmy choo dealsWitrynaβ-Naphthoflavone has been used: as aryl hydrocarbon receptor agonist to elucidate its effect on Cyp1A1 expression in embryos of transgenic cytochrome P450 1A1 (cyp1a) reporter zebrafish; as AhR agonists, to treat primary normal human epidermal keratinocytes (NHEKs) to study about aryl hydrocarbon receptor (AhR) activation by … jimmy choo designer wedding shoesWitrynaKup Teraz ⮞⮞⮞ ACM NovoPhane Lotion przeciw wypadaniu włosów 100 ml ️ Odbiór osobisty w aptece ☝ Świetne ceny i szybka dostawa! jimmy choo designer net worthWitrynaα-naphthoflavone in the solvent of choice, which should be purged with an inert gas. α-Naphthoflavone is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF). The solubility of α-naphthoflavone in these solvents is approximately 1, 10, and 20 mg/ml, respectively. α-Naphthoflavone is sparingly soluble in aqueous ... install slide in electric rangeWitrynaThe effect of beta-naphthoflavone (beta-NF) on several catalytic activities of cytochrome P450 (CYP) and phase II enzymes putatively controlled by [Ah]-receptor activation in the liver, heart and kidney of gilthead seabream, was investigated. In the liver, beta-NF treatment [intraperitoneal injectio … jimmy choo designer shoes songWitrynaFinally, Hepa-1 cells were treated with β-naphthoflavone (βNF) for 2–24 h and the level of AHR was quantified in cytosolic fractions using [125 I]iodo-7,8-dibromodibenzo-p-dioxin (Swanson and Perdew 1993). Specific binding to AHR was reduced by 62% following 12 h exposure to βNF, but then recovered to initial levels by 24 h. … install slickwraps macbook 12