WebFeb 25, 2024 · Microorganisms utilize electron bifurcating enzymes in metabolic pathways to carry out thermodynamically unfavorable reactions. Bifurcating FeFe-hydrogenases (HydABC) reversibly oxidize NADH (E'~-280 mV, under physiological conditions) and reduce protons to H 2 gas (E°'-414 mV) by coupling this endergonic reaction to the exergonic … WebMar 6, 2024 · As NADH is an important hydrogen/electron carrier in the electron transport chain, ... Integrated thermodynamic analysis of electron bifurcating [FeFe]-hydrogenase to inform anaerobic metabolism and H 2 production. Biochim Biophys Acta Bioenerg. 2024; 1861: 148087. 10.1016/j.bbabio.2024.148087.
A Bacterial Electron-bifurcating Hydrogenase* - Semantic Scholar
WebIn biochemistry, electron bifurcation (EB) refers to a system that enables an unfavorable transformation by coupling to a favorable transformation. Two electrons are involved: one flows to an acceptor with a "higher reduction potential and the other with a lower reduction potential" than the donor. The process is suspected of being common in ... WebOct 1, 2024 · Electron bifurcation is a biological energy conversion process that oxidizes a two-electron donor at medium potential, coupled to the reduction of a high- and a low-potential acceptor species. sia heart elastic
Energy conservation via electron bifurcating ferredoxin reduction and ...
WebElectron bifurcation plays a key role in anaerobic energy metabolism, but it is a relatively new discovery, and only limited mechanistic information is available on the diverse enzymes that employ it. Herein, we focused on the bifurcating electron transfer flavoprotein (ETF) from the hyperthermophilic archaeon Pyrobaculum aerophilum. The EtfABCX enzyme … WebMar 27, 2024 · The tetrameric cytoplasmic FeFe hydrogenase Hnd from Solidesulfovibrio fructosivorans (formely Desulfovibrio fructosovorans) catalyses H2 oxidation and couples the exergonic reduction of NAD+ to the endergonic reduction of a ferredoxin by using a flavin-based electron-bifurcating mechanism. Regarding its implication in the bacterial … WebDec 1, 2024 · Electron bifurcation thus harnesses the free energy of exergonic electron transfer to drive endergonic electron transfer. Q-based electron bifurcation occurs when … the pearl hotel spi